Chronic Myeloid Leukemia is a type of cancer that starts in certain cells that produce blood from the bone marrow. a genetic change occurs in an early (immature) version of myeloid cells (cells that produce red blood cells, platelets, and most types of white blood cells). this change is due to an abnormal gene called bcr-abl, which converts the cell into a leukemic cell .the leukemic cells grows and divides, accumulates in the bone marrow and spreads to the blood. during this time, the cells can also invade another parts of the body, including the spleen.
They are often imprecise:
The only risk factors for CML are:
Genetic testing will be performed to determine if the Philadelphia chromosome and / or the BCR-ABL gene is present. This type of test is used to confirm the diagnosis of CML.
The first treatment for CML is:
The only known cure for chronic myeloid leukemia is a bone marrow transplant or a stem cell transplant. However, most patients do not need a transplant because the drugs that attack the disease are effective.
There is no known way to prevent most cases of chronic myeloid leukemia. The only risk factor for chronic myeloid leukemia that can potentially be avoided is exposure to high doses of radiation, which only occurs in a few patients.